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ResMed AirMini HumidX Plus

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Prescription Not Required
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If you use the AirMini travel CPAP machine in a dry or high-altitude environment and experience dry mouth or nasal passages, the ResMed AirMini HumidX Plus offers a convenient way to add more moisture to the air you breathe while you sleep. It's a waterless heat and moisture exchanger (HME) — a disposable cartridge that inserts into the hose between the machine and your mask — and it adds more moisture to the air than the standard HumidX.

Is the HumidX Plus Right for You?

This is the right pick if you travel to dry or high-altitude destinations and find that standard humidification isn't enough to prevent dry mouth or nasal irritation. If you mainly use your AirMini in typical, everyday climates, the HumidX Standard is usually sufficient and is the lower-cost option. If you use the AirMini F20 full-face mask, neither this Plus version nor the Standard is compatible — you'll want the HumidX F20 instead.

Key Features at a Glance

  • Adds more moisture to the air than the HumidX Standard
  • No water to add or empty — convenient for travel
  • Purpose-built for low-humidity and high-altitude environments
  • Easy-to-replace disposable cartridge
  • Lightweight and portable

How the HumidX Plus Works

As you exhale, the HumidX Plus captures heat and moisture from your breath. On your next inhale, it releases that moisture back into the airflow, humidifying the air you're breathing without a water tank. The Plus version is built to retain and return more moisture than the Standard, which is what makes it a better fit for drier air.

Why Choose the HumidX Plus Over the Standard

Built Specifically for Dry and High-Altitude Air

Dry climates and higher altitudes both tend to pull more moisture out of the air you breathe, which can make standard humidification fall short. The HumidX Plus is designed with that specific scenario in mind, adding more moisture than the Standard version to help close that gap.

Still Waterless and Travel-Friendly

Even with the added humidification capacity, the HumidX Plus keeps the same waterless, no-tank convenience as the Standard version — nothing to fill, empty, or spill in transit.

Helps With Dryness and Irritation

If dry mouth or nasal passages are disrupting your AirMini therapy in a dry environment, the HumidX Plus is a targeted way to add back the moisture your standard setup might not be providing. Reducing that dryness and throat irritation supports more comfortable, consistent use of your therapy.

How to Use

  1. Insert the HumidX Plus into the hose connection point between your AirMini and mask.
  2. Connect your mask as usual.
  3. Start therapy — the HumidX Plus works automatically with each breath.

Replacement

Replace the HumidX Plus every 30 days, or sooner if it becomes visibly dirty or damaged.

Important Compatibility Notes

  • Not compatible with the AirMini F20 mask — see the HumidX F20 instead
  • Should not be used with heated hoses

Specifications

Spec

Detail

Brand

ResMed

Compatible machine

AirMini travel CPAP

Best suited for

Dry or high-altitude environments

Humidification type

Waterless heat and moisture exchanger (HME)

Recommended replacement

Every 30 days

Prescription required

No

HumidX Plus vs. HumidX Standard vs. HumidX F20

ResMed makes three HumidX variants, and it's easy to grab the wrong one: this Plus version is built for dry or high-altitude environments and adds more moisture than the Standard, which is designed for typical, everyday climates. Neither is compatible with the AirMini F20 mask — that mask requires the dedicated HumidX F20. Confirm your mask and typical travel climate before ordering to make sure you get the right one.

Complete Your AirMini Setup

Using the F20 full-face mask instead? See the HumidX F20 or the AirMini F20 Setup Pack with HumidX F20. Traveling somewhere more typical? Compare the lower-cost HumidX Standard. Round out your setup with the AirMini Filter and AirMini Tubing. Browse all AirMini Masks, or see more from the brand on the ResMed brand page.

Frequently Asked Questions

How is the HumidX Plus different from the Standard?

Both use the same waterless HME technology, but the Plus adds more moisture to the air, making it a better fit for dry or high-altitude environments where the Standard may not be enough.

Will this work with my AirMini F20 mask?

No. The HumidX Plus is not compatible with the AirMini F20 mask. Use the HumidX F20 instead.

How often do I need to replace it?

Every 30 days, or sooner if it becomes visibly dirty or damaged.

Can I use this with a heated hose?

No. The HumidX Plus should not be used with heated hoses.

Do I need this if I already use the HumidX Standard?

Only if you're finding the Standard insufficient — typically in dry, cold, or high-altitude conditions. For everyday use in typical climates, the Standard is usually enough and costs less.

Do I need a prescription to buy this?

No. This accessory does not require a prescription. A prescription is only needed for CPAP masks and machines.